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In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greatest frequency of decreased hepatic, renal or cardiac function, and of concomitant disease or other drug therapy.
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Treatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of C. difficile.
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Some patients have experienced considerable difficulty in tapering and discontinuing from alprazolam, especially those receiving higher doses for extended periods.
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This summary section refers to specific treatments under study in clinical trials, but it may not mention every new treatment being studied.
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Improvements in care have increased life expectancy in SCD, and it may be anticipated that stroke prophylaxis in older SCD patients will pose an increasing challenge in the future.
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MS CONTIN® Tablets are associated with typical opioid-related adverse experiences.

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By April, confirmed cases were also reported in the United States.
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After primary infection, cats shed millions of oocysts in their feces for about one to three weeks; the oocysts take one to five days to sporulate, which then can infect mice and birds (termed intermediate hosts) when these animals ingest water, plants, or soil containing the sporulated oocysts.
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Extracorporeal shockwave lithotripsy (ESWL): A device that generates shock waves is used to break gallstones up into tiny pieces.
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No mutagenic potential of haloperidol was found in the Ames Salmonella microsomal activation assay.
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The schizophrenic disorders are characterized in general by fundamental and characteristic distortions of thinking and perception, and affects that are inappropriate or blunted.
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Therefore, the dose of Humalog Mix50/50 should be given within 15 minutes before a meal.
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IN THIS ARTICLEDiabetic Foot Care OverviewDiabetic Foot Care CausesDiabetic Foot Care SymptomsWhen to Seek Medical CareExams and TestsDiabetic Foot Care TreatmentSelf-Care at HomeMedical TreatmentNext StepsFollow-upPreventionOutlookSynonyms and KeywordsAuthors and EditorsWhen to Seek Medical CareWrite down the patient's symptoms and be prepared to talk about them on the phone with a doctor.
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Indium In 111 Oxyquinoline labeled leukocytes should be given to a pregnant woman only if clearly needed.

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Inherited bleeding disorders (such as von Willebrand disease and hemophilia) may cause excessive or prolonged vaginal bleeding.
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As seen in the accompanying tables (TABLES 5 and 6), clinical failure represented a composite endpoint of breakthrough IFI, mortality and use of systemic antifungal therapy.
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In fact, the features of normal-tension glaucoma are similar to primary open-angle glaucoma (POAG), the most common form of glaucoma (see Primary Open-Angle Glaucoma).
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Many experts believe that cluster headache and migraine headache share a common cause that begins in the nerve that carries sensation from your head to your brain (trigeminal nerve) and ends with the blood vessels that surround your brain.
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Studies in asthmatic patients have shown a favorable ratio between topical anti-inflammatory activity and systemic corticosteroid effects over a wide range of doses from PULMICORT FLEXHALER or inhaled budesonide.
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Almost 8% of the women treated with Ellence survived with or without relapse over five years, whereas 70% of the women receiving CMF survived after five years.
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Because many drugs are excreted in human milk and because of the potential for serious adverse reactions to pergolide in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
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Loxapine should be used with extreme caution in patients with a history of convulsive disorders since it lowers the convulsive threshold.

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NeutroSpecTM [Technetium (99m Tc) fanolesomab] is intended for a single intravenous (IV) administration through an intravenous access that has been demonstrated to be patent, e.g., butterfly, running IV line, or equivalent injection system to assure that no dose infiltration occurs.
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The symptoms are persistent and in some patients appear irreversible.
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The definition of erectile dysfunction is "the inability to achieve or maintain an erection sufficient for satisfactory sexual performance.
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During cardiac catheterization, a thin, flexible tube called a catheter is put into a vein in the arm, groin (upper thigh), or neck and threaded to the heart.
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The patient’s bone marrow function should be monitored.
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Another drug widely used to treat motor neuron disease, gabapentin (Neurontin), has shown no positive effects on dementia.
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Reintroduction of EPZICOM or any other abacavir-containing product, even in patients who have no identified history or unrecognized symptoms of hypersensitivity to abacavir therapy, can result in serious or fatal hypersensitivity reactions.
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When standing quickly, it may take a second or two for the body to make adjustments to constrict blood vessels and push blood up to the brain.

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N Engl J Med.
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Rheumatoid arthritis should not be confused with other forms of arthritis, such as osteoarthritis or arthritis associated with infections.
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Bleeding after sexual relations or between menstrual periods Lower abdominal pain and burning pain during urination Discharge from the vaginaMen Like women, men who are infected may not show symptoms.
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Another team is studying the use of benign bacteria on a catheter to inhibit the growth of disease-causing bacteria.
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Elevations in BUN and serum uric acid have been reported.
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Occasional blurriness of vision may occur after eyedrops or ointments are placed in your eyes.
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Ongoing clinical trials for patients with cardiomyopathies are being conducted by the National Institutes of Health.
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Use in Patients with Congestive Heart Failure: Although acute hemodynamic studies in patients with congestive heart failure have shown that immediate-release DynaCirc® (isradipine) reduced afterload without impairing myocardial contractility, it has a negative inotropic effect at high doses in vitro and possibly in some patients.

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Its half-life, or time needed for the concentration of the drug in the blood to be reduced by half, is 5–7 hours.
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These doses are approximately 8 times the human subcutaneous dose of 1.0 U/kg/day for rats and equal to the human subcutaneous dose of 1.0 U/kg/day for rabbits, based on U/body surface area.
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In three clinical trials for which the data were pooled, 4 of 85 (5%) patients who received placebo, 10 of 86 (12%) who received <50 mg of Marplan per day, and 1 of 52 (2%) who received ≥50 mg of Marplan per day prematurely discontinued treatment.
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John's wort was no more effective for treating major depression of moderate severity than placebo.
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Patients with severely impaired renal function have been treated with cimetidine.
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Other causes of conjunctivitis include bacterial infection, allergic reactions, chemical or irritant exposures, and ocular drying or irritation.

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In transient insomnia, a 7.5 mg dose may be sufficient to improve sleep latency.
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The penicillinase-resistant penicillins are available for oral administration and for intramuscular and intravenous injection.
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In patients with hepatic dysfunction due to cirrhosis, levels of benazeprilat are essentially unaltered.
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The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition.
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Patients should be advised to adhere to dietary guidelines (see [#section-11 DOSAGE AND ADMINISTRATION]). Gastrointestinal events (see [#section-9 ADVERSE REACTIONS]) may increase when XENICAL is taken with a diet high in fat (>30% total daily calories from fat).
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Making food safe in the first place is a major effort, involving the farm and fishery, the production plant or factory, and many other points from the farm to the table.

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No evidence of induced endocrine dysfunction was found, and the condition remained unchanged or returned toward normal with continuing cimetidine treatment.
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Lumigan may gradually change eyelashes and vellus hair in the treated eye; these changes include increased length, thickness and number of lashes.
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Reported acute ingestions of up to 18 g orally have been associated with transient adverse effects similar to those encountered in normal clinical experience (see ADVERSE REACTIONS).
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Controlled clinical trials demonstrated that intranasal fluorocarbon-propelled ipratropium bromide does not alter physiologic nasal functions (e.g., sense of smell, ciliary beat frequency, mucociliary clearance, or the air conditioning capacity of the nose).
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Patients who develop complications of rhabdomyolysis often require hospitalization and monitoring.

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Individuals lucky enough to find a successful treatment for their symptoms can lead normal lives.
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The mean length of follow-up was 4.8 years.
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Currently, the majority of the US population has no immunity, vaccine is in short supply, and no effective treatment exists for the disease.
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IN THIS ARTICLESpitting Up in Infants OverviewSpitting Up in Infants CausesWhen to Seek Medical CareExams and TestsSpitting Up in Infants TreatmentSelf-Care at HomeMedical TreatmentMedicationsSynonyms and KeywordsAuthors and EditorsSpitting Up in Infants CausesWhen we eat or drink, food passes down the feeding tube or esophagus and into the stomach.

Avoid placing objects in the ear that can scrape or scratch the skin of the canal because this may cause an infection.
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The angioedema was diagnosed by procedures including abdominal CT scan or ultrasound, or at surgery, and symptoms resolved after stopping the ACE inhibitor.

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Although in controlled studies citalopram tablets have not been shown to impair psychomotor performance, any psychoactive drug may impair judgment, thinking or motor skills, and so patients should be cautioned about operating hazardous machinery, including automobiles, until they are reasonably certain that citalopram tablets therapy does not affect their ability to engage in such activities.
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The incidence and mortality figure for the U.S. are about half that of the rest of the world, a difference which can be attributed in part to the success of screening with the Pap smear.
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Healing is slow and may require skin grafting to cover the defect.
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The way the radiation therapy is given depends on the type and stage of the cancer being treated.
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IN THIS ARTICLELeukemia OverviewLeukemia CausesLeukemia SymptomsWhen to Seek Medical CareExams and TestsLeukemia TreatmentMedical TreatmentMedicationsSurgeryOther TherapyNext StepsFollow-upPreventionOutlookSupport Groups and CounselingFor More InformationWeb LinksSynonyms and KeywordsAuthors and EditorsViewer Comments: Leukemia - Symptoms ExperiencedLeukemia CausesThe exact cause of leukemia is unknown.
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Studies of nitroglycerin (an organic nitrate with a very short half-life) have shown that daily dose-free intervals of 10 to 12 hours are usually sufficient to minimize tolerance.

Chemotherapy after surgery can prolong survival for people whose cancer has spread to nearby lymph nodes.
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Although the mechanism of antiresorptive action is not completely understood, several factors are thought to contribute to this action.

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Manifestations of adrenal suppression in pediatric patients include linear growth retardation, delayed weight gain, low plasma cortisol levels, and absence of response to ACTH stimulation.
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Adverse reactions to anticholinergics in general may include xerostomia; decreased sweating; urinary hesitancy and retention; blurred vision; tachycardia; palpitations; dilation of the pupil; cycloplegia; increased ocular tension; loss of taste; headaches; nervousness; mental confusion; drowsiness; weakness; dizziness; insomnia; nausea; vomiting; constipation; bloated feeling; impotence; suppression of lactation; severe allergic reaction or drug idiosyncrasies including anaphylaxis, urticaria and other dermal manifestations.
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Fracture of the tibia and the fibula, after fixation in the operating room with metal rod and screws.
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In Table 2 for these endpoints, when read in combination with the non-contrast images, 0.1 mmol/kg MULTIHANCE provided a statistically significant improvement over baseline.
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Patients should be instructed to report events such as sleep-driving and other complex behaviors immediately to the prescriber.

The medication will not make you pain free, but it should make the pain tolerable.
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People with non-nephropathic or ocular cystinosis usually do not experience growth impairment or kidney malfunction.
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Similarly, it is not known which, if any, of these substances can usefully be removed from the body by hemodialysis.

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During meiosis I (also known as the first maturation division, or the reduction division), homologous chromosomes are separated (disjunction), reducing the number of chromosomes per nucleus (2n → n; 4c → 2c).
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Rifampin has been reported to possess immunosuppressive potential in rabbits, mice, rats, guinea pigs, human lymphocytes in vitro, and humans.
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The abnormal bone marrow cells may begin to grow out of control.
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Do not use soap, alcohol, or other solvents to remove the hydrogel because they may enhance the drug's ability to penetrate the skin.
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Abdominal examination (looking for pain and/or masses in the abdomen) and careful examination of the genitals and secondary sexual characteristics (breast development, pattern of hair growth) are very important, as is looking for signs of other disease (dry skin, abdominal obesity, stretch marks, abnormal facial features or other signs of genetic syndromes).
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Different skin areas can break out at different times, making it seem as if the rash is spreading.

Relapse during the double-blind phase was defined as the following conditions being met on two consecutive visits: (1) CGI-I ≥ 3; (2) CAPS-2 score increased by ≥ 30% and by ≥ 15 points relative to baseline; and (3) worsening of the patient's condition in the investigator's judgment.
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Depending upon the examination, the health care practitioner may take swabs of the vaginal discharge for culture or for examination under a microscope to help define the cause of the vaginal discharge.

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The renal clearance of desglymidodrine is of the order of 385 mL/minute, most, about 80%, by active renal secretion.
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Oblique-view chest x-ray films may improve the ability to detect central lesions on chest x-ray films.
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Researchers sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases conducted the Diabetes Prevention Program (DPP) to find the most effective ways to prevent or delay the onset of type 2 diabetes.
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Dermatologists are innovators of new immune enhancing treatments, like topical imiquimod for superficial cancers and injection immunotherapy for warts as discussed below.
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More commonly, hormone levels improve, but do not return to normal.

Aside from the direct brain tissue injury, increased pressure build-up within the skull can decrease the amount of blood flow to the brain causing anoxic or hypoxic damage.
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The most commonly observed adverse events that occurred in ≥ 5% of patients receiving AZILECT 1 mg (n=149) as adjunct to levodopa therapy participating in the double-blind, placebo-controlled trial (Study 1) and that were at least 1.5 times the incidence in the placebo group (n=159) in descending order of difference in incidence were dyskinesia, accidental injury, weight loss, postural hypotension, vomiting, anorexia, arthralgia, abdominal pain, nausea, constipation, dry mouth, rash, ecchymosis, somnolence and paresthesia.
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Fatal reactions have occurred in patients despite premedication.

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Stem cells (immature blood cells) are removed from the blood or bone marrow of the patient or a donor and are frozen and stored.
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Some people may have a racing heartbeat or feel dizzy or lightheaded just before they faint.
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Because of differences in the action of Humalog Mix50/50 and other insulins, care should be taken in patients in whom such potential side effects might be clinically relevant (e.g., patients who are fasting, have autonomic neuropathy, or are using potassium–lowering drugs or patients taking drugs sensitive to serum potassium level).
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The treatment schedule involved inhalation of Ca-DTPA 2 µmol/kg (0.11 MHD) 30 minutes after contamination followed by inhalation of Zn-DTPA 2 µmol/kg at approximately 6 hours, 1, 2, 3, and 6 days, then twice weekly to day 26 or day 27. The treatment regime reduced the lung deposit of plutonium and americium to 1-2% of that in untreated animals.
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Fish oil supplements have been shown to have some anti-inflammation properties, and increasing the dietary fish intake and/or taking fish oil capsules (omega-3 capsules) can sometimes reduce the inflammation of arthritis.
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Penetrating trauma may cause immediate, severe symptoms or only minor symptoms despite a potentially life-threatening injury.

Other clinical endpoints of the LIFE study were: total mortality, hospitalization for heart failure or angina pectoris, coronary or peripheral revascularization procedures, and resuscitated cardiac arrest.
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Some cephalic disorders occur when the cranial sutures (the fibrous joints that connect the bones of the skull) join prematurely.

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Each lobar bronchus branches into multiple tertiary (segmental) bronchi, each serving a bronchopulmonary segment.
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Several instances of trilineage bone marrow hypoplasia or aplasia resulting in pancytopenia, sometimes resulting in death, have been reported in postmarketing surveillance.
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Therefore, formoterol is given in combination with beta-blockers only in people with asthma who absolutely require the combination.
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If an allergic reaction to ofloxacin occurs, discontinue the drug.

Goiter: As described above, the pituitary will try to stimulate production of thyroid hormone in an underactive thyroid gland affected by Hashimoto's disease.
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Half of these patients had Type 1 diabetes (18/1285) and half had Type 2 (18/90) diabetes.
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Pictures are taken as the dye passes through the blood vessels in the retina.